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Issue 9, 2011
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Structure elucidation and biosynthesis of lysine-rich cyclic peptides in Xenorhabdus nematophila

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Abstract

Thirteen novel PAX (peptide-antimicrobial-Xenorhabdus) peptides were identified in Xenorhabdus nematophilaHGB081. Their structures including the absolute configuration were elucidated using a combination of labeling experiments, detailed MS/MS experiments, the advanced Marfey's method, and a detailed analysis of the biosynthesis gene cluster, which was identified as well.

Graphical abstract: Structure elucidation and biosynthesis of lysine-rich cyclic peptides in Xenorhabdus nematophila

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The article was received on 18 Jan 2011, accepted on 09 Feb 2011 and first published on 10 Feb 2011


Article type: Communication
DOI: 10.1039/C1OB05097D
Citation: Org. Biomol. Chem., 2011,9, 3130-3132
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    Structure elucidation and biosynthesis of lysine-rich cyclic peptides in Xenorhabdus nematophila

    S. W. Fuchs, A. Proschak, T. W. Jaskolla, M. Karas and H. B. Bode, Org. Biomol. Chem., 2011, 9, 3130
    DOI: 10.1039/C1OB05097D

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