Jump to main content
Jump to site search

Issue 3, 2011
Previous Article Next Article

Synthesis of difluoroaryldioxoles using BrF3

Author affiliations

Abstract

A novel synthesis of different aromatic and heteroaromatic difluorodioxole derivatives has been developed. The starting materials were catechols, which, after treatment with thiophosgene, formed at 0 °C the respective thiodioxoles. The latter were reacted for a short time with commercially available bromine trifluoride, producing potentially biologically important difluoroaryldioxoles in moderate to high yields.

Graphical abstract: Synthesis of difluoroaryldioxoles using BrF3

Back to tab navigation

Publication details

The article was received on 12 Aug 2010, accepted on 02 Nov 2010 and first published on 03 Dec 2010


Article type: Paper
DOI: 10.1039/C0OB00571A
Citation: Org. Biomol. Chem., 2011,9, 902-905
  •   Request permissions

    Synthesis of difluoroaryldioxoles using BrF3

    Y. Hagooly, M. J. Welch and S. Rozen, Org. Biomol. Chem., 2011, 9, 902
    DOI: 10.1039/C0OB00571A

Search articles by author

Spotlight

Advertisements