Jump to main content
Jump to site search

Issue 3, 2011
Previous Article Next Article

Nanoscale coordination polymers exhibiting luminescence properties and NMR relaxivity

Author affiliations

Abstract

This article presents the first example of ultra-small (3–4 nm) magneto-luminescent cyano-bridged coordination polymer nanoparticles Ln0.333+Gdx3+/[Mo(CN)8]3 (Ln = Eu (x = 0.34), Tb (x = 0.35)) enwrapped by a natural biocompatible polymer chitosan. The aqueous colloidal solutions of these nanoparticles present a luminescence characteristic of the corresponding lanthanides (5D07F0–4 (Eu3+) or the 5D47F6–2 (Tb3+)) under UV excitation and a green luminescence of the chitosan shell under excitation in the visible region. Magnetic Resonance Imaging (MRI) efficiency, i.e. the nuclear relaxivity, measurements performed for Ln0.333+Gdx3+/[Mo(CN)8]3nanoparticles show r1p and r2p relaxivities slightly higher than or comparable to the ones of the commercial paramagnetic compounds Gd-DTPA® or Omniscan® indicating that our samples may potentially be considered as a positive contrast agent for MRI. The in vitro studies performed on these nanoparticles show that they maybe internalized into human cancer and normal cells and well detected by fluorescence at the single cell level. They present high stability even at low pH and lack of cytotoxicity both in human cancer and normal cells.

Graphical abstract: Nanoscale coordination polymers exhibiting luminescence properties and NMR relaxivity

Back to tab navigation

Supplementary files

Publication details

The article was received on 22 Sep 2010, accepted on 01 Dec 2010 and first published on 24 Jan 2011


Article type: Paper
DOI: 10.1039/C0NR00709A
Citation: Nanoscale, 2011,3, 1200-1210
  •   Request permissions

    Nanoscale coordination polymers exhibiting luminescence properties and NMR relaxivity

    E. Chelebaeva, J. Larionova, Y. Guari, R. A. S. Ferreira, L. D. Carlos, A. A. Trifonov, T. Kalaivani, A. Lascialfari, C. Guérin, K. Molvinger, L. Datas, M. Maynadier, M. Gary-Bobo and M. Garcia, Nanoscale, 2011, 3, 1200
    DOI: 10.1039/C0NR00709A

Search articles by author

Spotlight

Advertisements