Carba-LNA modified siRNAs targeting HIV-1 TAR region downregulate HIV-1 replication successfully with enhanced potency†
Abstract
The conformationally-locked
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* Corresponding authors
a Institute of Molecular Medicine, BIPL, Building – B, Ist Floor, Block – EP & GP, Salt Lake Electronics Complex, Sector –V, Kolkata, India
b Institute of Molecular Medicine, International Biotech Park, Genesis Campus, Phase II Opp Infosys, Tal Mulshi Hinjewadi, Pune, India
c
Program of Chemical Biology, Institute of Cell and Molecular Biology, Box 581, Biomedical Centre, Uppsala University, Uppsala, Sweden
E-mail:
jyoti@boc.uu.se
Fax: +46-18-554495
Tel: +46-18-4714577
The conformationally-locked
S. Dutta, N. Bhaduri, N. Rastogi, S. G. Chandel, J. K. Vandavasi, R. S. Upadhayaya and J. Chattopadhyaya, Med. Chem. Commun., 2011, 2, 206 DOI: 10.1039/C0MD00225A
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