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Issue 6, 2011
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Translating cancer research by synthetic biology

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Abstract

Synthetic biology concerns applying engineering principles to biological systems. Engineering properties such as fine tuning, novel specificity, and modularity could be components of a synthetic toolkit that can be exploited to explore various issues in cancer research such as elucidation of mechanisms and pathways, creating new diagnostic tools and novel therapeutic approaches. A repertoire of synthetic biology toolkits involving DNA, RNA and protein bio-parts, have been applied to address the issues of drug target identification, drug discovery and therapeutic treatment in cancer research, thereby projecting a new dimension in oncology research.

Graphical abstract: Translating cancer research by synthetic biology

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Publication details

The article was received on 15 Jan 2011, accepted on 24 Feb 2011 and first published on 24 Mar 2011


Article type: Review Article
DOI: 10.1039/C1MB05016H
Citation: Mol. BioSyst., 2011,7, 1802-1810
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    Translating cancer research by synthetic biology

    S. Shankar and M. R. Pillai, Mol. BioSyst., 2011, 7, 1802
    DOI: 10.1039/C1MB05016H

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