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Issue 17, 2011
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Bio-inspired, efficient, artificial lung employing air as the ventilating gas

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Abstract

Artificial lungs have recently been utilized to rehabilitate patients suffering from lung diseases. However, significant advances in gas exchange, biocompatibility, and portability are required to realize their full clinical potential. Here, we have focused on the issues of gas exchange and portability and report a small-scale, microfabricated artificial lung that uses new mathematical modeling and a bio-inspired design to achieve oxygen exchange efficiencies much larger than current devices, thereby enabling air to be utilized as the ventilating gas. This advancement eliminates the need for pure oxygen required by conventional artificial lung systems and is achieved through a device with feature sizes and structure similar to that in the natural lung. This advancement represents a significant step towards creating the first truly portable and implantable artificial lung systems for the ambulatory care of patients suffering from lung diseases.

Graphical abstract: Bio-inspired, efficient, artificial lung employing air as the ventilating gas

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Publication details

The article was received on 10 Jan 2011, accepted on 17 May 2011 and first published on 14 Jul 2011


Article type: Paper
DOI: 10.1039/C1LC20020H
Citation: Lab Chip, 2011,11, 2901-2909
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    Bio-inspired, efficient, artificial lung employing air as the ventilating gas

    J. A. Potkay, M. Magnetta, A. Vinson and B. Cmolik, Lab Chip, 2011, 11, 2901
    DOI: 10.1039/C1LC20020H

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