Issue 3, 2011

Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol–ene orthogonal coupling

Abstract

We describe a general user-friendly platform for fine-tuning the drug release properties of low-molecular-weight hydrogels by a combination of supramolecular co-assembly of complementary molecular structures and controlled photochemical thiol–ene cross-linking. Other critical features such as thermomechanical stability and morphology of the nanostructured hydrogels are also tailored by this approach.

Graphical abstract: Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol–ene orthogonal coupling

Supplementary files

Article information

Article type
Communication
Submitted
08 Oct 2010
Accepted
03 Nov 2010
First published
22 Nov 2010

J. Mater. Chem., 2011,21, 641-644

Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol–ene orthogonal coupling

D. D. Díaz, E. Morin, E. M. Schön, G. Budin, A. Wagner and J. Remy, J. Mater. Chem., 2011, 21, 641 DOI: 10.1039/C0JM03399E

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