Intracellular mapping with SERS-encoded gold nanostars

Laura Rodríguez-Lorenzo; Zeljka Krpetic; Silvia Barbosa; Ramón A. Alvarez-Puebla; Luis M. Liz-Marzán; Ian A. Prior; Mathias Brust

doi:10.1039/C1IB00029B

Intracellular mapping with SERS-encoded gold nanostars†

Laura Rodríguez-Lorenzo,^ab Zeljka Krpetic,^b Silvia Barbosa,^a Ramón A. Alvarez-Puebla,*^a Luis M. Liz-Marzán,*^a Ian A. Prior^c and Mathias Brust^b

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^a Departamento de Quimica-Fisica and Unidad Asociada CSIC-Universidade de Vigo, 36310 Vigo, Spain
E-mail: ramon.alvarez@uvigo.es, lmarzan@uvigo.es
Web: http://webs.uvigo.es/coloides/nano

^b Centre for Nanoscale Science, Department of Chemistry, University of Liverpool, Crown Street, Liverpool L69 7ZD, United Kingdom

^c School of Biomedical Sciences, Department of Physiology, University of Liverpool, Liverpool L69 3BX, United Kingdom

Abstract

Here we report on the design, synthesis and application of small, highly bright, star-shaped SERS encoded single nanoparticles with the ability of providing an optical signal upon excitation with near infrared light. These particles are colloidally stable, fully biocompatible and can be internalized into living cells for intracellular imaging.

Integrative Biology

Intracellular mapping with SERS-encoded gold nanostars†

Abstract

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