Gold        nanorods-based FRET assay for ultrasensitive detection of Hg2+

Guozhen Chen; Yan Jin; Lin Wang; Jing Deng; Chengxiao Zhang

doi:10.1039/C1CC15084G

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Gold nanorods-based FRET assay for ultrasensitive detection of Hg²⁺†

Guozhen Chen,^ab Yan Jin,*^ab Lin Wang,^ab Jing Deng^ab and Chengxiao Zhang^ab

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* Corresponding authors

^a Key Laboratory of Applied Surface and Colloid Chemistry, Shaanxi Normal University, Ministry of Education, Xi'an, PR China
E-mail: jinyan@snnu.edu.cn
Fax: 86-29-85307774

^b Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, PR China

Abstract

A fluorescence method for detecting mercury ion in a homogeneous medium is proposed with gold nanorods (GNRs) as a fluorescence quencher on the basis of the fluorescence resonance energy transfer (FRET). Under the optimum conditions, the method exhibits a dynamic response range from 10 pM to 5 nM with a detection limit of 2.4 pM.

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Article information

DOI: https://doi.org/10.1039/C1CC15084G
Article type: Communication
Submitted: 16 Aug 2011
Accepted: 05 Oct 2011
First published: 25 Oct 2011

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Chem. Commun., 2011,47, 12500-12502

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Gold nanorods-based FRET assay for ultrasensitive detection of Hg²⁺

G. Chen, Y. Jin, L. Wang, J. Deng and C. Zhang, Chem. Commun., 2011, 47, 12500 DOI: 10.1039/C1CC15084G

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