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Department of Biopharmaceutical Sciences, University of Illinois at Chicago, 833 S. Wood St. Chicago, USA
E-mail: sphong@uic.edu
; Fax: +1 312-996-0098
; Tel: +1 312-413-8294
b
Department of Chemistry, University of Illinois at Chicago, 845 W. Taylor St. Chicago, USA
E-mail: pkral@uic.edu
; Fax: +1 312-996-0431
; Tel: +1 312-996-6319
Chem. Commun., 2011,47, 10302-10304
DOI:
10.1039/C1CC14331J
Received
18 Jul 2011,
Accepted
05 Aug 2011
First published online
22 Aug 2011
PEGylated dendron coils (PDCs) were investigated as a novel potential nanocarrier platform. PDCs self-assembled into micelles at lower CMCs than linear copolymer counterparts by 1–2 orders of magnitude, due to the unique architecture of dendrons. MD simulations also supported thermodynamically favourable self-assembly mediated by dendrons.
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