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Issue 31, 2011
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New insight on 2-naphthylmethyl (NAP) ether as a protecting group in carbohydrate synthesis: a divergent approach towards a high-mannose type oligosaccharide library

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Abstract

A new method for selective cleavage of 2-naphthylmethyl (NAP) ether utilizing 10–20 molar excess of HF/pyridine in toluene was revealed and strategically applied to a divergent approach towards generation of a high-mannose type oligosaccharide library.

Graphical abstract: New insight on 2-naphthylmethyl (NAP) ether as a protecting group in carbohydrate synthesis: a divergent approach towards a high-mannose type oligosaccharide library

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Publication details

The article was received on 02 Jun 2011, accepted on 22 Jun 2011 and first published on 07 Jul 2011


Article type: Communication
DOI: 10.1039/C1CC13264D
Citation: Chem. Commun., 2011,47, 8952-8954
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    New insight on 2-naphthylmethyl (NAP) ether as a protecting group in carbohydrate synthesis: a divergent approach towards a high-mannose type oligosaccharide library

    Y. Li, B. Roy and X. Liu, Chem. Commun., 2011, 47, 8952
    DOI: 10.1039/C1CC13264D

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