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Issue 37, 2011
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Efficient biotinylation of methacryloyl-functionalized nonadherent cells for formation of cell microarrays

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Abstract

In order to obtain cell microarrays formed with human promyelocytic leukemia cells (HL-60), biotinylation of methacryloyl-functionalized HL-60 cells was performed via a thiol–ene reaction with thiol-terminated 4-arm poly(ethylene glycol) (PEG410K-SH). Biotinylated HL-60 cells were selectively adhered onto an avidin-patterned surface with high viability.

Graphical abstract: Efficient biotinylation of methacryloyl-functionalized nonadherent cells for formation of cell microarrays

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Publication details

The article was received on 19 May 2011, accepted on 02 Aug 2011 and first published on 19 Aug 2011


Article type: Communication
DOI: 10.1039/C1CC12948A
Citation: Chem. Commun., 2011,47, 10329-10331
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    Efficient biotinylation of methacryloyl-functionalized nonadherent cells for formation of cell microarrays

    Y. Iwasaki and T. Ota, Chem. Commun., 2011, 47, 10329
    DOI: 10.1039/C1CC12948A

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