Issue 13, 2011
From the journal:

Chemical Communications

Catalytic enantioselective synthesis of A-86929, a dopamine D1 agonist†

Saumen Hajra*a  and  Sukanta Bara  

* Corresponding authors

a Department of Chemistry, Indian Institute of Technology Kharagpur, Kharagpur 721302, India
E-mail: shajra@chem.iitkgp.ernet.in
Fax: +91 3222 255303
Tel: +91 3222 283340

Abstract

A-86929, a dopamine D1 agonist was synthesized with 95% ee in five steps with overall yield of 56% viacatalytic enantioselective one-pot aziridination followed by Friedel–Crafts cyclization and a mild Pictet–Spengler cyclization protocol.

Graphical abstract: Catalytic enantioselective synthesis of A-86929, a dopamine D1 agonist

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C1CC10263J
Article type
Communication
Submitted
14 Jan 2011
Accepted
25 Jan 2011
First published
14 Feb 2011

Chem. Commun., 2011,47, 3981-3982

Permissions

Request permissions

Catalytic enantioselective synthesis of A-86929, a dopamine D1 agonist

S. Hajra and S. Bar, Chem. Commun., 2011, 47, 3981 DOI: 10.1039/C1CC10263J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements