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Issue 15, 2011
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Catalytic asymmetric syntheses of isoxazoline-N-oxides under phase-transfer conditions

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Abstract

Catalytic asymmetric syntheses of various isoxazoline-N-oxides have been accomplished by asymmetric phase-transfer conjugate addition of bromomalonate to nitroolefins and subsequent ring-closing O-alkylation.

Graphical abstract: Catalytic asymmetric syntheses of isoxazoline-N-oxides under phase-transfer conditions

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Publication details

The article was received on 25 Dec 2010, accepted on 13 Jan 2011 and first published on 01 Feb 2011


Article type: Communication
DOI: 10.1039/C0CC05786J
Citation: Chem. Commun., 2011,47, 4358-4360
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    Catalytic asymmetric syntheses of isoxazoline-N-oxides under phase-transfer conditions

    T. Kano, A. Yamamoto, S. Song and K. Maruoka, Chem. Commun., 2011, 47, 4358
    DOI: 10.1039/C0CC05786J

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