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Issue 17, 2011
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Reactive oxygen species in photochemistry of the red fluorescent protein “Killer Red”

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Abstract

The fluorescent protein aptly named “Killer Red” (KRed) is capable of killing transfected cells and inactivating fused proteins upon exposure to visible light in the presence of oxygen. We have investigated the source of the bioactive species through a variety of photophysical and photochemical techniques. Our results indicate a Type I (electron transfer mediated) photosensitizing mechanism.

Graphical abstract: Reactive oxygen species in photochemistry of the red fluorescent protein “Killer Red”

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Publication details

The article was received on 21 Dec 2010, accepted on 09 Feb 2011 and first published on 28 Feb 2011


Article type: Communication
DOI: 10.1039/C0CC05713D
Citation: Chem. Commun., 2011,47, 4887-4889
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    Reactive oxygen species in photochemistry of the red fluorescent protein “Killer Red”

    R. B. Vegh, K. M. Solntsev, M. K. Kuimova, S. Cho, Y. Liang, B. L. W. Loo, L. M. Tolbert and A. S. Bommarius, Chem. Commun., 2011, 47, 4887
    DOI: 10.1039/C0CC05713D

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