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Issue 6, 2011
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Efficient and general synthesis of oxazino[4,3-a]indoles by cascade addition-cyclization reactions of (1H-indol-2-yl)methanols and vinyl sulfonium salts

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Abstract

An efficient and general approach to oxazino[4,3-a]indole architectures is described. The addition-cyclization cascade of (1H-indol-2-yl)methanols with vinyl sulfonium salts affords oxazino[4,3-a]indole derivatives in high yields.

Graphical abstract: Efficient and general synthesis of oxazino[4,3-a]indoles by cascade addition-cyclization reactions of (1H-indol-2-yl)methanols and vinyl sulfonium salts

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Publication details

The article was received on 13 Sep 2010, accepted on 16 Nov 2010 and first published on 30 Nov 2010


Article type: Communication
DOI: 10.1039/C0CC03823G
Citation: Chem. Commun., 2011,47, 1869-1871
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    Efficient and general synthesis of oxazino[4,3-a]indoles by cascade addition-cyclization reactions of (1H-indol-2-yl)methanols and vinyl sulfonium salts

    J. An, N. Chang, L. Song, Y. Jin, Y. Ma, J. Chen and W. Xiao, Chem. Commun., 2011, 47, 1869
    DOI: 10.1039/C0CC03823G

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