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Department of Biochemistry, UT Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, USA
E-mail: Chuo.Chen@UTSouthwestern.edu
; Fax: 214 648 0320
; Tel: 214 648 5048
Chem. Commun., 2011,47, 427-429
DOI:
10.1039/C0CC02214D
Received
29 Jun 2010,
Accepted
03 Sep 2010
First published online
16 Sep 2010
We propose herein an alternative biosynthetic pathway for palau'amine in order to resolve the stereochemical issue from the original Kinnel–Scheuer hypothesis. Furthermore, we use this revised hypothesis as a guide toward the laboratory synthesis of palau'amine.
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