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Issue 11, 2011
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Cascade polycyclisations in natural product synthesis

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The efficient, stereocontrolled construction of polycyclic ring systems has long presented a formidable challenge to synthetic chemists. Cascade reactions offer a ‘quick fix’—building multiple rings in a single step—and often dramatically shorten a synthetic route. In this Emerging Area article, a selection of the most recent and impressive examples of applications of this tactic to natural product synthesis are discussed, which demonstrate the ambition and achievements of the modern synthetic chemist.

Graphical abstract: Cascade polycyclisations in natural product synthesis

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Publication details

The article was received on 08 Feb 2011, accepted on 24 Mar 2011 and first published on 28 Apr 2011

Article type: Emerging Area
DOI: 10.1039/C1OB05212H
Citation: Org. Biomol. Chem., 2011,9, 3997-4006
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    Cascade polycyclisations in natural product synthesis

    E. A. Anderson, Org. Biomol. Chem., 2011, 9, 3997
    DOI: 10.1039/C1OB05212H

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