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Efficient chemo-enzymatic synthesis of endomorphin-1 using organic solvent stable proteases to green the synthesis of the peptide

Honglin Sun,a   Bingfang He,*ab   Jiaxing Xu,a   Bin Wua and   Pingkai Ouyangab  
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a
College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology, 5 Xinmofan Road, Nanjing, China
E-mail: bingfanghe@njut.edu.cn;
Fax: +86 25 83172069 ;
Tel: +86 25 83172069
b
State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing University of Technology, 5 Xinmofan Road, Nanjing, China
Green Chem., 2011,13, 1680-1685

DOI: 10.1039/C1GC15042A
Received 12 Jan 2011, Accepted 15 Mar 2011
First published online 11 Apr 2011
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