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Issue 1, 2011
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Rapid release of plasmid DNA from polyelectrolyte multilayers: A weak poly(acid) approach

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Abstract

We demonstrate an approach to the assembly of DNA-containing polyelectrolyte multilayers that can be used to promote rapid release of DNA from surfaces. The approach is based on layer-by-layer incorporation of poly(acrylic acid) to promote rapid erosion in physiologically relevant media.

Graphical abstract: Rapid release of plasmid DNA from polyelectrolyte multilayers: A weak poly(acid) approach

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Publication details

The article was received on 30 Jul 2010, accepted on 10 Nov 2010 and first published on 23 Nov 2010


Article type: Communication
DOI: 10.1039/C0CC02926B
Citation: Chem. Commun., 2011,47, 550-552
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    Rapid release of plasmid DNA from polyelectrolyte multilayers: A weak poly(acid) approach

    R. M. Flessner, Y. Yu and D. M. Lynn, Chem. Commun., 2011, 47, 550
    DOI: 10.1039/C0CC02926B

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