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Issue 39, 2011
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A facile and sensitive immunoassay for the detection of alpha-fetoprotein using gold-coated magnetic nanoparticle clusters and dynamic light scattering

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Abstract

A facile and sensitive immunoassay protocol for the detection of alpha-fetoprotein (AFP) was developed using gold-coated iron oxide magnetic nanoclusters and dynamic light scattering (DLS) methods. The increase in the average particle size due to AFP-mediated aggregation was measured using DLS, and the detection limit was better than 0.01 ng mL−1.

Graphical abstract: A facile and sensitive immunoassay for the detection of alpha-fetoprotein using gold-coated magnetic nanoparticle clusters and dynamic light scattering

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Publication details

The article was received on 05 Jul 2011, accepted on 25 Aug 2011 and first published on 09 Sep 2011


Article type: Communication
DOI: 10.1039/C1CC14024H
Citation: Chem. Commun., 2011,47, 11047-11049
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    A facile and sensitive immunoassay for the detection of alpha-fetoprotein using gold-coated magnetic nanoparticle clusters and dynamic light scattering

    C. Chun, J. Joo, D. Kwon, C. S. Kim, H. J. Cha, M. Chung and S. Jeon, Chem. Commun., 2011, 47, 11047
    DOI: 10.1039/C1CC14024H

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