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Issue 16, 2010
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Peptide conjugate hydrogelators

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Abstract

Molecular gelators are currently receiving a great deal of attention. These are small molecules which, under the appropriate conditions, assemble in solution to, in the majority of cases, give long fibrillar structures which entangle to form a three-dimensional network. This immobilises the solvent, resulting in a gel. Such gelators have potential application in a number of important areas from drug delivery to tissue engineering. Recently, the use of peptide-conjugates has become prevalent with oligopeptides (from as short as two amino acids in length) conjugated to a polymer, alkyl chain or aromatic group such as naphthalene or fluorenylmethoxycarbonyl (Fmoc) being shown to be effective molecular gelators. The field of gelation is extremely large; here we focus our attention on the use of these peptide-conjugates as molecular hydrogelators.

Graphical abstract: Peptide conjugate hydrogelators

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Publication details

The article was received on 14 Jan 2010, accepted on 19 Mar 2010 and first published on 16 Apr 2010


Article type: Review Article
DOI: 10.1039/C000813C
Citation: Soft Matter, 2010,6, 3707-3721
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    Peptide conjugate hydrogelators

    D. J. Adams and P. D. Topham, Soft Matter, 2010, 6, 3707
    DOI: 10.1039/C000813C

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