Biomimetically relevant self-condensations of C5 units derived from lysine

Rim Salame; Edmond Gravel; Pascal Retailleau; Erwan Poupon

doi:10.1039/B926786G

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Biomimetically relevant self-condensations of C₅ units derived from lysine†

Rim Salame,^a Edmond Gravel,‡^a Pascal Retailleau^b and Erwan Poupon*^a

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* Corresponding authors

^a Université Paris-Sud, Faculté de Pharmacie, Laboratoire de Pharmacognosie associé au CNRS, UMR 8076 BioCIS, 5, rue Jean-Baptiste Clément, Châtenay-Malabry, France
E-mail: erwan.poupon@u-psud.fr
Fax: +33-146835399

^b Institut de Chimie des Substances Naturelles CNRS, Service de Cristallochimie, bâtiment 27, Avenue de la Terrasse, Gif-sur-Yvette CEDEX, France

Abstract

In various conditions, dimerization of pentanedial-derived units gives rise to interesting skeletons, which are reminiscent of alkaloids known to be biosynthesized in Nature via lysine metabolism.

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Article information

DOI: https://doi.org/10.1039/B926786G
Article type: Paper
Submitted: 22 Dec 2009
Accepted: 16 Mar 2010
First published: 01 Apr 2010

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Org. Biomol. Chem., 2010,8, 2522-2528

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Biomimetically relevant self-condensations of C₅ units derived from lysine

R. Salame, E. Gravel, P. Retailleau and E. Poupon, Org. Biomol. Chem., 2010, 8, 2522 DOI: 10.1039/B926786G

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Organic & Biomolecular Chemistry