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Issue 12, 2010
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Recent advances in DNA-based directed assembly on surfaces

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In the last decade, “small” and “integrated” have been keywords in the field of device fabrication as the desire to exploit nanoscale phenomena and make electronic, photonic and magnetic arrays has grown. In an effort to improve resolution and control costs, much work has been dedicated to developing alternatives to conventional microfabrication technology. For this purpose, biomolecular assembly and DNA nanotechnology in particular are appealing owing to their inherent size and capacity for molecular recognition. Herein, we review recent achievements in DNA-based directed assembly on substrates. These include novel methods for patterning and depositing nanomaterials on DNA-modified surfaces as well as using synthetic DNA nanostructures such as DNA tiles and origami as templates to direct the assembly of nanoscale components. Particular attention is paid to integrating self-assembly with top-down lithography, and some possible directions for future work are discussed.

Graphical abstract: Recent advances in DNA-based directed assembly on surfaces

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The article was received on 22 Jun 2010, accepted on 21 Jul 2010 and first published on 13 Sep 2010

Article type: Review Article
DOI: 10.1039/C0NR00430H
Citation: Nanoscale, 2010,2, 2530-2537
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    Recent advances in DNA-based directed assembly on surfaces

    A. M. Hung, H. Noh and J. N. Cha, Nanoscale, 2010, 2, 2530
    DOI: 10.1039/C0NR00430H

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