Jump to main content
Jump to site search

Issue 5, 2010
Previous Article Next Article

Data-mining patent literature for novel chemical reagents for use in medicinal chemistry design

Author affiliations

Abstract

The properties of any molecule are fixed at the point of design. Since reliance on commercially available reagents sets to probe SAR relationships may result in incomplete interrogation of property space, efforts to pursue novel proprietary reagent collections are of clear benefit. One such approach based on fragmentation and analysis of molecules described in patent and medicinal chemistry literature is described, highlighting an example of key secondary amines with potential for broad applicability across medicinal chemistry.

Graphical abstract: Data-mining patent literature for novel chemical reagents for use in medicinal chemistry design

Back to tab navigation

Publication details

The article was received on 02 Sep 2010, accepted on 21 Sep 2010 and first published on 13 Oct 2010


Article type: Concise Article
DOI: 10.1039/C0MD00148A
Citation: Med. Chem. Commun., 2010,1, 331-338
  •   Request permissions

    Data-mining patent literature for novel chemical reagents for use in medicinal chemistry design

    J. G. Kettle, R. A. Ward and E. Griffen, Med. Chem. Commun., 2010, 1, 331
    DOI: 10.1039/C0MD00148A

Search articles by author

Spotlight

Advertisements