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Issue 14, 2010
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Hydrophilic PDMS microchannels for high-throughput formation of oil-in-water microdroplets and water-in-oil-in-water double emulsions

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Abstract

Here we present a novel surface modification method based on the sequential layer-by-layer deposition of polyelectrolytes yielding hydrophilic microchannels in PDMS-based microfluidic devices. The coatings are long-term stable and allow for the generation of monodisperse oil-in-water microdroplets even several months after the channel surface treatment. Due to the robustness of the polyelectrolyte multilayers ultra-high flow rates can be applied, making high-throughput droplet formation in the jetting mode possible. Furthermore, we successfully used our method to selectively modify the surface properties in certain areas of assembled microchannels. The resulting partially hydrophilic, partially hydrophobic microfluidic devices allow for the production of monodisperse water-in-oil-in-water double emulsions.

Graphical abstract: Hydrophilic PDMS microchannels for high-throughput formation of oil-in-water microdroplets and water-in-oil-in-water double emulsions

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Publication details

The article was received on 09 Mar 2010, accepted on 15 Apr 2010 and first published on 05 May 2010


Article type: Paper
DOI: 10.1039/C004046K
Citation: Lab Chip, 2010,10, 1814-1819
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    Hydrophilic PDMS microchannels for high-throughput formation of oil-in-water microdroplets and water-in-oil-in-water double emulsions

    W. C. Bauer, M. Fischlechner, C. Abell and W. T. S. Huck, Lab Chip, 2010, 10, 1814
    DOI: 10.1039/C004046K

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