Issue 1, 2010
From the journal:

Lab on a Chip

Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody†

Jason P. Gleghorn,a   Erica D. Pratt,b   Denise Denning,c   He Liu,d   Neil H. Bander,d   Scott T. Tagawa,e   David M. Nanus,e   Paraskevi A. Giannakakoue  and  Brian J. Kirby*a  

* Corresponding authors

a Sibley School of Mechanical & Aerospace Engineering, College of Engineering, Cornell University, Ithaca, NY, USA
E-mail: bk88@cornell.edu
Tel: +6072554379

b Department of Biomedical Engineering, College of Engineering, Cornell University, Ithaca, NY, USA

c Department of Physical Sciences, Dublin City University, Dublin, Ireland

d Department of Urology, Weill Cornell Medical College, Cornell University, New York, NY, USA

e Division of Hematology & Oncology, Weill Cornell Medical College, Cornell University, New York, NY, USA

Abstract

Geometrically enhanced differential immunocapture (GEDI) and an antibody for prostate-specific membrane antigen (PSMA) are used for high-efficiency and high-purity capture of prostate circulating tumor cells from peripheral whole blood samples of castrate-resistant prostate cancer patients.

Graphical abstract: Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody

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Article information

DOI
https://doi.org/10.1039/B917959C
Article type
Communication
Submitted
01 Sep 2009
Accepted
29 Oct 2009
First published
16 Nov 2009

Lab Chip, 2010,10, 27-29

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Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody

J. P. Gleghorn, E. D. Pratt, D. Denning, H. Liu, N. H. Bander, S. T. Tagawa, D. M. Nanus, P. A. Giannakakou and B. J. Kirby, Lab Chip, 2010, 10, 27 DOI: 10.1039/B917959C

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