Morphology and structure of organosilica hybrid particles derived from tetramethoxysilane and vinyltrimethoxysilanevia a catalyst-free sol–gel route

Abstract

Organosilica hybrid particles were derived for the first time from a catalyst-free neutral sol–gel system of vinyltrimethoxysilane, tetramethoxysilane, ethanol, and water and consisted of T species (CH₂CH–Si(–O–Si)_n(OH, OCH₃)_3−n, n = 2 and 3) and Q species (Si(–O–Si)_n(OH, OCH₃)_4−n, n = 2, 3, and 4). After combined with poly(methylmethacrylate) and CaCl₂, they induced deposition of bioactive apatite in the Kokubo's simulated body fluid and are applicable for bone regeneration.