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Issue 36, 2010
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A general glycomimetic strategy yields non-carbohydrate inhibitors of DC-SIGN

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Abstract

Shikimic acid can be transformed into monovalent and multivalent glycomimetics that target different members of the C-type lectin class, including DC-SIGN, a dendritic cell lectin that facilitates HIV transmission.

Graphical abstract: A general glycomimetic strategy yields non-carbohydrate inhibitors of DC-SIGN

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Publication details

The article was received on 08 Apr 2010, accepted on 21 Jun 2010 and first published on 18 Aug 2010


Article type: Communication
DOI: 10.1039/C0CC00830C
Citation: Chem. Commun., 2010,46, 6747-6749
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    A general glycomimetic strategy yields non-carbohydrate inhibitors of DC-SIGN

    K. C. A. Garber, K. Wangkanont, E. E. Carlson and L. L. Kiessling, Chem. Commun., 2010, 46, 6747
    DOI: 10.1039/C0CC00830C

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