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Issue 23, 2010
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Total synthesis of (+)-stachyflin: a potential anti-influenza A virus agent

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Abstract

The first enantioselective total synthesis of (+)-stachyflin, a potential anti-influenza A virus agent, was achieved; the method features a BF3·Et2O-induced domino epoxide-opening/rearrangement/cyclization reaction to stereoselectively form the requisite pentacyclic ring system in one step.

Graphical abstract: Total synthesis of (+)-stachyflin: a potential anti-influenza A virus agent

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Publication details

The article was received on 06 Jan 2010, accepted on 04 Mar 2010 and first published on 01 Apr 2010


Article type: Communication
DOI: 10.1039/C000193G
Citation: Chem. Commun., 2010,46, 4055-4057
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    Total synthesis of (+)-stachyflin: a potential anti-influenza A virus agent

    K. Watanabe, J. Sakurai, H. Abe and T. Katoh, Chem. Commun., 2010, 46, 4055
    DOI: 10.1039/C000193G

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