Issue 3, 2010
From the journal:

Chemical Communications

Electrochemical evidences in oxidation of acetaminophen in the presence of glutathione and N-acetylcysteine†‡

Hasan Shayani-Jama  and  Davood Nematollahi*a  

* Corresponding authors

a Faculty of Chemistry, f Bu-Ali-Sina University, Hamedan, Iran
E-mail: nemat@basu.ac.ir
Fax: +98-811-8257407

Abstract

Electrochemical oxidation of acetaminophen has been studied in the presence of glutathione and acetylcysteine. Our results indicate that N-acetyl-p-benzoquinone-imine (NAPQI) participates in a catalytic reaction with glutathione and N-acetylcysteine. Also, the observed homogeneous rate constants of the reaction of NAPQI with glutathione and acetylcysteine were estimated.

Graphical abstract: Electrochemical evidences in oxidation of acetaminophen in the presence of glutathione and N-acetylcysteine

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Article information

DOI
https://doi.org/10.1039/B916458H
Article type
Communication
Submitted
10 Aug 2009
Accepted
17 Nov 2009
First published
02 Dec 2009

Chem. Commun., 2010,46, 409-411

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Electrochemical evidences in oxidation of acetaminophen in the presence of glutathione and N-acetylcysteine

H. Shayani-Jam and D. Nematollahi, Chem. Commun., 2010, 46, 409 DOI: 10.1039/B916458H

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