Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 24, 2009
Previous Article Next Article

Nanofiber-supported phospholipid bilayers

Author affiliations

Abstract

The natural cell cytoskeleton provides critical mechanical support for lipid bilayers using a network of actin fibers. As a step towards fabricating artificial cells, functional nanofiber networks were created to mimic the chemical and mechanical environment provided by the actin network. Lipid bilayers were formed on a random nanofiber mat made from ∼131 nm diameter polycaprolactam nanofibers modified to be highly hydrophilic by coating with 6.6 nm of silica (SiO2). The nanofiber-supported bilayers were characterized using fluorescence recovery after photobleaching (FRAP) and electrophysiological recordings and found to be comparable to bilayer recordings from natural membranes. The nanofiber-supported bilayers were also more stable than conventional, unsupported, black lipid bilayers.

Graphical abstract: Nanofiber-supported phospholipid bilayers

Back to tab navigation
Please wait while Download options loads

Publication details

The article was received on 13 Feb 2009, accepted on 28 Aug 2009 and first published on 19 Oct 2009


Article type: Paper
DOI: 10.1039/B903048D
Citation: Soft Matter, 2009,5, 5037-5041
  •   Request permissions

    Nanofiber-supported phospholipid bilayers

    F. Yi, J. Xu, A. M. Smith, A. N. Parikh and D. A. LaVan, Soft Matter, 2009, 5, 5037
    DOI: 10.1039/B903048D

Search articles by author