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Issue 28, 2009
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Copper-catalyzed cyclization reactions for the synthesis of alkaloids

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Abstract

Copper-mediated Ullmann type transformations have recently evolved as useful and valuable synthetic tools in organic synthesis. If newly developed catalytic systems are readily available, inexpensive, and tolerate most functional groups, they also provide new opportunities in natural product synthesis since they allow new and efficient retrosynthetic disconnections. They are also especially convenient for the development of straightforward cyclization and macrocyclization procedures. The present article showcases some examples of copper-catalyzed cyclization reactions for the synthesis of alkaloids we have recently developed.

Graphical abstract: Copper-catalyzed cyclization reactions for the synthesis of alkaloids

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Publication details

The article was received on 19 Mar 2009, accepted on 21 Apr 2009 and first published on 18 May 2009


Article type: Feature Article
DOI: 10.1039/B905601G
Citation: Chem. Commun., 2009,0, 4166-4175
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    Copper-catalyzed cyclization reactions for the synthesis of alkaloids

    G. Evano, M. Toumi and A. Coste, Chem. Commun., 2009, 0, 4166
    DOI: 10.1039/B905601G

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