Issue 6, 2009
From the journal:

Chemical Communications

Fluorescent assay of DNA hybridization with label-free molecular switch: reducing background-signal and improving specificity by using carbon nanotubes†

Yue Liu,a   Yongxiang Wang,a   Jianyu Jin,a   Hao Wang,a   Ronghua Yang*ab  and  Weihong Tan*bc  

* Corresponding authors

a Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China
E-mail: Yangrh@pku.edu.cn
Fax: +86-10-62751708

b Biomedical Engineering Center, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China

c Center for Research at the Bio/Nano Interface, Department of Chemistry and Department of Physiology and Functional Genomics, Shands Cancer Center, University of Florida, Gainesville, Florida, USA
E-mail: tan@chem.ufl.edu

Abstract

Using classic DNA-intercalating dye and carbon nanotubes, a simple, but efficient, method for fluorescent detection of DNA hybridization has been developed.

Graphical abstract: Fluorescent assay of DNA hybridization with label-free molecular switch: reducing background-signal and improving specificity by using carbon nanotubes

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Article information

DOI
https://doi.org/10.1039/B819526A
Article type
Communication
Submitted
03 Nov 2008
Accepted
12 Dec 2008
First published
07 Jan 2009

Chem. Commun., 2009, 665-667

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Fluorescent assay of DNA hybridization with label-free molecular switch: reducing background-signal and improving specificity by using carbon nanotubes

Y. Liu, Y. Wang, J. Jin, H. Wang, R. Yang and W. Tan, Chem. Commun., 2009, 665 DOI: 10.1039/B819526A

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