Jump to main content
Jump to site search

Issue 23, 2008
Previous Article Next Article

Stereoselective synthesis of the hormonally active (25S)-Δ7-dafachronic acid, (25S)-Δ4-dafachronic acid, (25S)-dafachronic acid, and (25S)-cholestenoic acid

Author affiliations

Abstract

We report a stereoselective synthesis of the (25S)-cholestenoic-26-acids which are highly efficient ligands for the hormonal receptor DAF-12 in Caenorhabditis elegans.

Graphical abstract: Stereoselective synthesis of the hormonally active (25S)-Δ7-dafachronic acid, (25S)-Δ4-dafachronic acid, (25S)-dafachronic acid, and (25S)-cholestenoic acid

Back to tab navigation

Supplementary files

Publication details

The article was received on 29 Aug 2008, accepted on 02 Oct 2008 and first published on 17 Oct 2008


Article type: Communication
DOI: 10.1039/B815064H
Citation: Org. Biomol. Chem., 2008,6, 4293-4295
  •   Request permissions

    Stereoselective synthesis of the hormonally active (25S)-Δ7-dafachronic acid, (25S)-Δ4-dafachronic acid, (25S)-dafachronic acid, and (25S)-cholestenoic acid

    R. Martin, F. Däbritz, E. V. Entchev, T. V. Kurzchalia and H. Knölker, Org. Biomol. Chem., 2008, 6, 4293
    DOI: 10.1039/B815064H

Search articles by author

Spotlight

Advertisements