Issue 2, 2007
From the journal:

Green Chemistry

A highly efficient and green method for the synthesis of 3,4-dihydropyrimidin-2-ones and 1,5-benzodiazepines catalyzed by dodecyl sulfonic acid in water†

Saikat Das Sharma,a   Pranjal Gogoia  and  Dilip Konwar*a  

* Corresponding authors

a Synthetic Organic Chemistry Division, Regional Research Laboratory, Jorhat, India
E-mail: dkonwar@yahoo.co.uk
Fax: +9103763370011
Tel: +91-9435351864

Abstract

A simple, efficient, mild and green method has been developed for the synthesis of 3,4-dihydropyrimidin-2-ones employing dodecyl sulfonic acid as an excellent surfactant-type Brønsted acid catalyst in aqueous media at room temperature. The catalyst was shown to be equally effective for the synthesis of 1,5-benzodiazepines under the same reaction condition.

Graphical abstract: A highly efficient and green method for the synthesis of 3,4-dihydropyrimidin-2-ones and 1,5-benzodiazepines catalyzed by dodecyl sulfonic acid in water

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Article information

DOI
https://doi.org/10.1039/B611327C
Article type
Paper
Submitted
07 Aug 2006
Accepted
26 Oct 2006
First published
09 Nov 2006

Green Chem., 2007,9, 153-157

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A highly efficient and green method for the synthesis of 3,4-dihydropyrimidin-2-ones and 1,5-benzodiazepines catalyzed by dodecyl sulfonic acid in water

S. D. Sharma, P. Gogoi and D. Konwar, Green Chem., 2007, 9, 153 DOI: 10.1039/B611327C

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