Issue 36, 2007
From the journal:

Chemical Communications

Novel application of Leuckart–Wallach reaction for synthesis of tetrahydro-1,4-benzodiazepin-5-ones library†

Sung-Chan Leea  and  Seung Bum Park*a  

* Corresponding authors

a Department of Chemistry, Seoul National University, Seoul, Korea
E-mail: sbpark@snu.ac.kr
Fax: (+82) 28844025
Tel: (+82) 28809090

Abstract

A novel and efficient strategy has been developed to synthesize privileged tetrahydro-1,4-benzodiazepines with excellent yields and purities; this synthetic pathway was established by the revitalization of the Leuckart–Wallach (LW) reaction via solid-phase synthesis.

Graphical abstract: Novel application of Leuckart–Wallach reaction for synthesis of tetrahydro-1,4-benzodiazepin-5-ones library

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Article information

DOI
https://doi.org/10.1039/B709768A
Article type
Communication
Submitted
27 Jun 2007
Accepted
13 Jul 2007
First published
08 Aug 2007

Chem. Commun., 2007, 3714-3716

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Novel application of Leuckart–Wallach reaction for synthesis of tetrahydro-1,4-benzodiazepin-5-ones library

S. Lee and S. B. Park, Chem. Commun., 2007, 3714 DOI: 10.1039/B709768A

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