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Issue 36, 2007
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Novel application of Leuckart–Wallach reaction for synthesis of tetrahydro-1,4-benzodiazepin-5-ones library

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Abstract

A novel and efficient strategy has been developed to synthesize privileged tetrahydro-1,4-benzodiazepines with excellent yields and purities; this synthetic pathway was established by the revitalization of the Leuckart–Wallach (LW) reaction via solid-phase synthesis.

Graphical abstract: Novel application of Leuckart–Wallach reaction for synthesis of tetrahydro-1,4-benzodiazepin-5-ones library

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Publication details

The article was received on 27 Jun 2007, accepted on 13 Jul 2007 and first published on 08 Aug 2007


Article type: Communication
DOI: 10.1039/B709768A
Citation: Chem. Commun., 2007, 3714-3716
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    Novel application of Leuckart–Wallach reaction for synthesis of tetrahydro-1,4-benzodiazepin-5-ones library

    S. Lee and S. B. Park, Chem. Commun., 2007, 3714
    DOI: 10.1039/B709768A

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