Issue 43, 2007

An alkoxide-directed alkyne–allene cross-coupling for stereoselective synthesis of 1,4-dienes

Abstract

A titanium alkoxide-mediated convergent coupling between internal alkynes and allenes is described for the regio- and stereocontrolled synthesis of substituted acyclic 1,4-dienes.

Graphical abstract: An alkoxide-directed alkyne–allene cross-coupling for stereoselective synthesis of 1,4-dienes

Supplementary files

Article information

Article type
Communication
Submitted
31 May 2007
Accepted
09 Aug 2007
First published
23 Aug 2007

Chem. Commun., 2007, 4531-4533

An alkoxide-directed alkyneallene cross-coupling for stereoselective synthesis of 1,4-dienes

H. L. Shimp and G. C. Micalizio, Chem. Commun., 2007, 4531 DOI: 10.1039/B708256H

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