Issue 36, 2007
From the journal:

Chemical Communications

A dual near-infrared pH fluorescent probe and its application in imaging of HepG2 cells†

Bo Tang,*a   Xia Liu,a   Kehua Xu,a   Hui Huang,a   Guiwen Yangb  and  Liguo Anb  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Engineering Research Center of Pesticide and Medicine Intermediate Clean Production, Shandong Normal University, Jinan 250014, P. R. China
E-mail: tangb@sdnu.edu.cn
Fax: +86-531-86180017
Tel: +86-531-86180010

b College of Life Science, Shandong Normal University, Jinan 250014, P. R. China
E-mail: yanggw@sdnu.edu.cn
Fax: +86-531-86180107
Tel: +86-531-86180143

Abstract

A dual near-infrared pH fluorescent probe has been designed, synthesized and applied to HepG2 cells, with a pKa value of 5.14 under acidic conditions and 11.31 under basic conditions, which is valuable for studying acidic organelles in living cells and pH changes in chemical systems.

Graphical abstract: A dual near-infrared pH fluorescent probe and its application in imaging of HepG2 cells

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Article information

DOI
https://doi.org/10.1039/B707173F
Article type
Communication
Submitted
14 May 2007
Accepted
27 Jun 2007
First published
09 Jul 2007

Chem. Commun., 2007, 3726-3728

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A dual near-infrared pH fluorescent probe and its application in imaging of HepG2 cells

B. Tang, X. Liu, K. Xu, H. Huang, G. Yang and L. An, Chem. Commun., 2007, 3726 DOI: 10.1039/B707173F

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