Issue 26, 2007
From the journal:

Chemical Communications

DMT-MM mediated functionalisation of the non-reducing end of glycosaminoglycans†

Emiliano Gemma,a   Alison N. Hulme,*a   Astrid Jahnke,a   Lan Jin,a   Malcolm Lyon,b   Ralf M. Müllera  and  Dušan Uhrín*a  

* Corresponding authors

a School of Chemistry, University of Edinburgh, West Mains Road, Edinburgh, UK
E-mail: Alison.Hulme@ed.ac.uk; Dusan.Uhrin@ed.ac.uk
Fax: +44 131 650 4743; +44 131 650 7155
Tel: +44 131 650 4711; +44 131 650 7061

b Cancer Research UK Glyco-Oncology Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, UK

Abstract

Efficient functionalisation of the non-reducing end of uronic acid derivatives and glycosaminoglycan-derived disaccharides using peptide coupling has been achieved, mediated by the water-soluble agent DMT-MM.

Graphical abstract: DMT-MM mediated functionalisation of the non-reducing end of glycosaminoglycans

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Article information

DOI
https://doi.org/10.1039/B617038B
Article type
Communication
Submitted
22 Nov 2006
Accepted
13 Mar 2007
First published
16 Apr 2007

Chem. Commun., 2007, 2686-2688

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DMT-MM mediated functionalisation of the non-reducing end of glycosaminoglycans

E. Gemma, A. N. Hulme, A. Jahnke, L. Jin, M. Lyon, R. M. Müller and D. Uhrín, Chem. Commun., 2007, 2686 DOI: 10.1039/B617038B

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