Issue 9, 2007

The effect of steric bulk in Sonogashira coupling reactions

Abstract

The rates of Sonogashira coupling reactions using [Pd–PR3] complexes depend on a combination of the steric bulk of phosphines and substrates; however, below a critical cone angle of ca. 170° the catalytic activity drops drastically.

Graphical abstract: The effect of steric bulk in Sonogashira coupling reactions

Supplementary files

Article information

Article type
Communication
Submitted
14 Nov 2006
Accepted
29 Nov 2006
First published
11 Dec 2006

Chem. Commun., 2007, 972-974

The effect of steric bulk in Sonogashira coupling reactions

M. an der Heiden and H. Plenio, Chem. Commun., 2007, 972 DOI: 10.1039/B616608C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements