Issue 8, 2007
From the journal:

Chemical Communications

Thiazolium-derived N-heterocyclic carbene-catalyzed cross-coupling of aldehydes with unactivated imines†

Gong-Qiang Li,a   Li-Xin Daia  and  Shu-Li You*a  

* Corresponding authors

a State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, P. R. China
E-mail: slyou@mail.sioc.ac.cn
Fax: (+86) 21-54925087

Abstract

Cross-coupling of aromatic aldehydes or benzoins with unactivated imines catalyzed by an N-heterocyclic carbene (NHC) affords α-amino ketones smoothly.

Graphical abstract: Thiazolium-derived N-heterocyclic carbene-catalyzed cross-coupling of aldehydes with unactivated imines

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Article information

DOI
https://doi.org/10.1039/B611646A
Article type
Communication
Submitted
11 Aug 2006
Accepted
03 Nov 2006
First published
23 Nov 2006

Chem. Commun., 2007, 852-854

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Thiazolium-derived N-heterocyclic carbene-catalyzed cross-coupling of aldehydes with unactivated imines

G. Li, L. Dai and S. You, Chem. Commun., 2007, 852 DOI: 10.1039/B611646A

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