Issue 46, 2007
From the journal:

Chemical Communications

Chimeric peptide beacons: a direct polypeptide analog of DNA molecular beacons†

Kenneth J. Oh,a   Kevin J. Cash,b   Arica A. Lubina  and  Kevin W. Plaxco*ac  

* Corresponding authors

a Department of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, CA, USA
E-mail: oh@chem.ucsb.edu, alubin@chem.ucsb.edu
Fax: (805) 893-4120
Tel: (805) 893-5845

b Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, CA, USA
E-mail: kcash@engineering.ucsb.edu
Fax: (805) 893-4120
Tel: (805) 893-5845

c Interdepartmental Program in Biomolecular Science and Engineering, University of California, Santa Barbara, Santa Barbara, CA, USA
E-mail: kwp@chem.ucsb.edu
Fax: (805) 893-4120
Tel: (805) 893-5558

Abstract

We have developed a new biosensor architecture, which is comprised of a polypeptide–peptide nucleic acid tri-block co-polymer and which we have termed chimeric peptide beacons (CPB), that generates an optical output via a mechanism analogous to that employed in DNA-based molecular beacons.

Graphical abstract: Chimeric peptide beacons: a direct polypeptide analog of DNA molecular beacons

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B709776J
Article type
Communication
Submitted
30 Jun 2007
Accepted
20 Sep 2007
First published
26 Oct 2007

Chem. Commun., 2007, 4869-4871

Permissions

Request permissions

Chimeric peptide beacons: a direct polypeptide analog of DNA molecular beacons

K. J. Oh, K. J. Cash, A. A. Lubin and K. W. Plaxco, Chem. Commun., 2007, 4869 DOI: 10.1039/B709776J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements