Issue 4, 2006
From the journal:

Chemical Communications

Coupling of permeabilized microorganisms for efficient enantioselective reduction of ketone with cofactor recycling†

Jie Zhang,a   Bernard Witholta  and  Zhi Li*a  

* Corresponding authors

a Institute of Biotechnology, ETH-Hönggerberg, Zurich, Switzerland
E-mail: zhi@biotech.biol.ethz.ch
Fax: +41 1 633 1051
Tel: +41 1 633 3811

Abstract

A novel, simple and efficient cofactor recycling method for enantioselective bioreduction has been developed by the use of permeabilized cells of a reductase-containing microorganism and a glucose dehydrogenase-containing microorganism.

Graphical abstract: Coupling of permeabilized microorganisms for efficient enantioselective reduction of ketone with cofactor recycling

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Article information

DOI
https://doi.org/10.1039/B515721H
Article type
Communication
Submitted
08 Nov 2005
Accepted
28 Nov 2005
First published
12 Dec 2005

Chem. Commun., 2006, 398-400

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Coupling of permeabilized microorganisms for efficient enantioselective reduction of ketone with cofactor recycling

J. Zhang, B. Witholt and Z. Li, Chem. Commun., 2006, 398 DOI: 10.1039/B515721H

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