Ammonium carbamate; mild, selective and efficient ammonia source for preparation of β-amino-α,β-unsaturated esters at room temperature
Abstract
Ammonium carbamate can be used as a very effective reagent for preparation of different substituted β-amino-α,β-unsaturated esters in methanol at room temperature. The product is isolated without aqueous work-up in high purity and excellent yield. The method is simple and easily scaled-up.