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Issue 47, 2005
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Inactivation of human angiotensin converting enzyme by copper peptide complexes containing ATCUN motifs

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Abstract

The copper complex [KGHK-Cu]+ demonstrates catalytic inactivation of human angiotensin converting enzyme at sub-saturating concentrations, under oxidative conditions, with an observed rate constant k ∼ 2.9 ± 0.5 × 10−2 min−1.

Graphical abstract: Inactivation of human angiotensin converting enzyme by copper peptide complexes containing ATCUN motifs

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Publication details

The article was received on 03 Aug 2005, accepted on 21 Sep 2005 and first published on 21 Oct 2005


Article type: Communication
DOI: 10.1039/B511081E
Citation: Chem. Commun., 2005,0, 5916-5918
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    Inactivation of human angiotensin converting enzyme by copper peptide complexes containing ATCUN motifs

    N. H. Gokhale and J. A. Cowan, Chem. Commun., 2005, 0, 5916
    DOI: 10.1039/B511081E

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