Issue 27, 2005

Ruthenium-catalysed asymmetric hydrogenation of ketones using QUINAPHOS as the ligand

Abstract

Highly enantioselective ruthenium-catalysed hydrogenation of aromatic ketones is achieved with (Ra,SC)-QUINAPHOS in the presence of achiral and chiral diamines as co-catalysts.

Graphical abstract: Ruthenium-catalysed asymmetric hydrogenation of ketones using QUINAPHOS as the ligand

Article information

Article type
Communication
Submitted
13 Apr 2005
Accepted
18 May 2005
First published
09 Jun 2005

Chem. Commun., 2005, 3460-3462

Ruthenium-catalysed asymmetric hydrogenation of ketones using QUINAPHOS as the ligand

S. Burk, G. Franciò and W. Leitner, Chem. Commun., 2005, 3460 DOI: 10.1039/B505195A

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