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Issue 23, 2005
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The use of a continuous flow-reactor employing a mixed hydrogen–liquid flow stream for the efficient reduction of imines to amines

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Abstract

Imines have been reduced to amines in high yield, and with excellent chemoselectivity, by catalytic hydrogenation in a continuous flow-reactor, utilising an electrochemically-generated hydrogen source to produce a mixed hydrogen–liquid flow stream.

Graphical abstract: The use of a continuous flow-reactor employing a mixed hydrogen–liquid flow stream for the efficient reduction of imines to amines

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Publication details

The article was received on 07 Apr 2005, accepted on 21 Apr 2005 and first published on 17 May 2005


Article type: Communication
DOI: 10.1039/B504854K
Citation: Chem. Commun., 2005, 2909-2911
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    The use of a continuous flow-reactor employing a mixed hydrogen–liquid flow stream for the efficient reduction of imines to amines

    S. Saaby, K. R. Knudsen, M. Ladlow and S. V. Ley, Chem. Commun., 2005, 2909
    DOI: 10.1039/B504854K

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