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Issue 16, 2005
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Cyclopentane-modified PNA improves the sensitivity of nanoparticle-based scanometric DNA detection

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Abstract

trans-Cyclopentane-modified PNA has been successfully utilized as a target capture strand to improve the detection limit of a known DNA detection assay, and provide high levels of mismatch discrimination.

Graphical abstract: Cyclopentane-modified PNA improves the sensitivity of nanoparticle-based scanometric DNA detection

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Publication details

The article was received on 06 Dec 2004, accepted on 11 Feb 2005 and first published on 09 Mar 2005


Article type: Communication
DOI: 10.1039/B418383E
Citation: Chem. Commun., 2005,0, 2101-2103
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    Cyclopentane-modified PNA improves the sensitivity of nanoparticle-based scanometric DNA detection

    J. K. Pokorski, J. Nam, R. A. Vega, C. A. Mirkin and D. H. Appella, Chem. Commun., 2005, 0, 2101
    DOI: 10.1039/B418383E

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