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Issue 15, 2004
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Lipase catalysed Michael addition of secondary amines to acrylonitrile

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Abstract

A new enzymatic process is described. Different preparations of lipase B from Candida antarctica are able to catalyse Michael-type addition of secondary amines to acrylonitrile. This new reaction widens the applicability of these biocatalysts in organic synthesis.

Graphical abstract: Lipase catalysed Michael addition of secondary amines to acrylonitrile

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Publication details

The article was received on 13 Feb 2004, accepted on 11 Jun 2004 and first published on 28 Jun 2004


Article type: Communication
DOI: 10.1039/B402244K
Citation: Chem. Commun., 2004,0, 1724-1725
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    Lipase catalysed Michael addition of secondary amines to acrylonitrile

    O. Torre, I. Alfonso and V. Gotor, Chem. Commun., 2004, 0, 1724
    DOI: 10.1039/B402244K

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